Well the alchemist in Solitude is pretty nice to my npc when I go there to sell my dragon scales/bones to her.
It's a shame you got booted from the Guild... things were going so well.
I'm really surprised no one has mentioned Rune, of the Thieves Guild. He's genuinely, honestly one of THE nicest NPCs in the damn game.
Scouts-many-marshes. He only asks for equality and peace. And all he gets is prejudice and hate. It's a shame.