Well, we've got a new patch coming out. I didn't see that this was specifically addressed, but I'd download it anyway when it's available on the consoles and see if it tweaks anything for you.
ive found that installing the game makes it less glitchy but the real thing is that you need to finish each quest as you start it.
I heard there are some really bad glitches and bugs in some peoples games. Thankfully the only glitch I have in mine is the Breeze Home weapon racks wont work. I cant download my game to my console (360) because we have the 4GB one. I think we are getting more memory soon though. Ive heard both good and bad things about the new update such as the kill cam. I haven't been really been paying attention to it, but I think I should start.
Well Its a bummer that you didn't have any earlier saves or this could have been redone pretty easy.